Fluorodibromoacetic acid ethyl ester
ethyl dibromofluoroacetate
CAS: 565-53-7
Molecular Formula: C4H5Br2FO2
Fluorodibromoacetic acid ethyl ester - Names and Identifiers
Fluorodibromoacetic acid ethyl ester - Physico-chemical Properties
| Molecular Formula | C4H5Br2FO2 |
| Molar Mass | 263.89 |
| Density | 1.894 |
| Melting Point | 157-161°C |
| Boling Point | 82 °C |
| Flash Point | 82°C/33mm |
| Water Solubility | Miscible with most organic solvents. Immiscible with water. |
| Appearance | clear liquid |
| Color | Colorless to Light yellow |
| BRN | 1762048 |
| Refractive Index | 1.4633 |
| Physical and Chemical Properties | Boiling point 82. Density 1.894. |
Fluorodibromoacetic acid ethyl ester - Risk and Safety
| Risk Codes | R21/22 - Harmful in contact with skin and if swallowed. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S23 - Do not breathe vapour. |
| UN IDs | 1760 |
| HS Code | 29159000 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | II |
Fluorodibromoacetic acid ethyl ester - Introduction
Ethyl dibromofluoroacetate (ethyl dibromofluoroacetate) is an organic compound with the chemical formula C4H6Br2F2O2. It is a colorless liquid with a pungent odor at room temperature. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Odor: pungent pungent odor
-Density: 1.921g/cm3
-Boiling point: 160-163 ℃
-Melting point:-29 ℃
-Solubility: miscible with ethanol and ether, insoluble in water
Use:
- ethyl dibromofluoroacetate is often used as a reagent in organic synthesis. It can be used as an esterification reagent, an acylation reagent, a nucleophilic substitution reagent, and the like.
-It is also used for some synthesis in the field of pesticides and pharmaceuticals.
Preparation Method:
The preparation method of-ethyl dibromofluoroacetate usually involves the reaction of diethyl difluoroacetate with hydrobromic acid and an acid catalyst. Specific steps are as follows:
1. Heat and mix diethyl difluoroacetic acid with hydrobromic acid.
2. add an appropriate amount of acid catalyst (such as sulfuric acid).
3. The reaction is carried out at an appropriate temperature.
4. Filtration or distillation to obtain pure ethyl dibromofluoroacetate.
Safety Information:
- ethyl dibromofluoroacetate is an irritating chemical substance. Protective measures should be paid attention to during use, such as wearing chemical protective gloves, goggles and protective clothing.
-Avoid breathing gas, touching skin, entering eyes or swallowing.
-During the operation, ensure that it is carried out in a well-ventilated place to avoid the accumulation of steam.
-If inadvertently exposed to this substance, immediately rinse the contaminated area with plenty of water and seek medical help if necessary.
Nature:
-Appearance: colorless liquid
-Odor: pungent pungent odor
-Density: 1.921g/cm3
-Boiling point: 160-163 ℃
-Melting point:-29 ℃
-Solubility: miscible with ethanol and ether, insoluble in water
Use:
- ethyl dibromofluoroacetate is often used as a reagent in organic synthesis. It can be used as an esterification reagent, an acylation reagent, a nucleophilic substitution reagent, and the like.
-It is also used for some synthesis in the field of pesticides and pharmaceuticals.
Preparation Method:
The preparation method of-ethyl dibromofluoroacetate usually involves the reaction of diethyl difluoroacetate with hydrobromic acid and an acid catalyst. Specific steps are as follows:
1. Heat and mix diethyl difluoroacetic acid with hydrobromic acid.
2. add an appropriate amount of acid catalyst (such as sulfuric acid).
3. The reaction is carried out at an appropriate temperature.
4. Filtration or distillation to obtain pure ethyl dibromofluoroacetate.
Safety Information:
- ethyl dibromofluoroacetate is an irritating chemical substance. Protective measures should be paid attention to during use, such as wearing chemical protective gloves, goggles and protective clothing.
-Avoid breathing gas, touching skin, entering eyes or swallowing.
-During the operation, ensure that it is carried out in a well-ventilated place to avoid the accumulation of steam.
-If inadvertently exposed to this substance, immediately rinse the contaminated area with plenty of water and seek medical help if necessary.
Last Update：2024-04-09 15:17:58
